Agmatine is part of a group of compounds known as polyamines, alphatic amines which play multiple physiological roles in tissue growth and differentiation, body weight increment, brain organization, molecular mechanisms of hormonal action, intracellular signaling, and extracellular paracrine communication. The most well-studied and known polyamines are putrescine (PUT), spermidine (SPD), and spermine (SPM) and agmatine. Agmatine itself is naturally produced in the body by the breakdown of arginine. Paradoxically, the studied effects of agmatine not only appear to mimic those of its parent compound arginine, but in many cases, surpass it. These effects include an increase in localized bloodflow (better plasma delivery), dilation of the vasculature (expanding of blood vessels), and increased nutrient delivery.