Natarajan MacuSeal™

Dehydrated Amniotic Membrane for Retinal Surgery

An innovation by Dr. Sundaram Natarajan Powered by Akriti® – Simplifying Eye Care

Product Overview

Natarajan MacuSeal™ is a biologically active, dehydrated amniotic membrane (AM) designed specifically for retinal applications. Sourced from the innermost layer of the placenta, it offers a regenerative scaffold that supports healing in complex retinal surgeries.

 Key Features

✅ Anti-inflammatory & anti-fibrotic properties

✅ Promotes epithelial healing and tissue recovery

✅ Immune-privileged to minimize adjacent tissue reaction

✅ Scaffold for cellular adhesion, proliferation, and migration

✅ ISO 10993 Biocompatibility Tested

✅ Sterilization & Viral Inactivation Validated

✅ Robust In Vitro Characterization: SEM, SDS-PAGE, Histology, Cell Culture, DNA Residue Analysis

✅ GMP Certified | CDSCO Approved | ISO 9001 Registered

 Clinical Applications

Macular Hole (MH) Closure

• Ideal for refractory, large, or high-myopia-associated MHs

• Inlay (plug) or overlay technique based on surgical preference

• Scaffold for gliosis and photoreceptor migration

Retinal Detachment Repair

• Adjunct in cases involving PVR, giant retinal tears, or posterior pole defects

• Barrier against subretinal fibrosis and RPE migration

Available Sizes

 Future Directions

• Stem cell enhancement & bioengineering potential

• Biodegradable and non-toxic for long-term safety

• Expanding therapeutic applications in retinal regeneration

Specifications: