Creatine is perhaps the most studied and verified of all dietary supplements, earning its moniker as the, Ògrandfather of supplements.Ó Through a number of enzymatic and cellular steps, creatine is first metabolized into a compound known as phosophocreatine, and eventually into a compound known as ATP (adenosine triphosphate) Ð the so-called, Òenergy currencyÓ of the human body. As a dietary supplement, the use of creatine over extended periods of time has been linked to a wide-range of physiological benefits, including: cell volumization, increased delivery of plasma (blood) nutrients to the cell, an increase in skeletal muscle total mass and protein synthesis, decrease in muscular fatigue, and increased endurance.