PLS1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34145-50, RA34145-100

Citations, Manuals and MSDS Available upon request.

Background: cofactor:Calcium.,function:May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.,function:May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. May contribute to cytokine-regulated cell proliferation and differentiation.,induction:By phosphorylation by PKC. Induced by INFB1 in response to a viral infection.,online information:Scramblase entry,PTM:Known to be palmitoylated at one, yet undefined, site.,similarity:Belongs to the phospholipid scramblase family.,subunit:Interacts with ABL.,tissue specificity:Expressed in platelets, erythrocyte membranes, lymphocytes, spleen, thymus, prostate, testis, uterus, intestine, colon, heart, placenta, lung, liver, kidney and pancreas. Not detected in brain and skeletal muscle.,

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 5359

Protein MW (KDa): 34

SWISS: O15162

Source: Rabbit

Research Use Only