Tecovirimat, also known as SIGA-246 and ST-246, is a core protein cysteine protease inhibitor potentially for treatment of smallpox infection. Tecovirimat is a novel antiviral that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs. Tecovirimat has shown efficacy in all small animal and nonhuman primate prophylaxis and therapeutic efficacy models of poxvirus-induced disease tested to date.

Product information

CAS Number: 869572-92-9

Molecular Weight: 376.33

Formula: C19H15F3N2O3

Synonym:

ST-246

Chemical Name: N-[(1R,2R,6S,7S,8S,10R)-3,5-dioxo-4-azatetracyclo[5.3.2.0²,⁶.0⁸,¹⁰]dodec-11-en-4-yl]-4-(trifluoromethyl)benzamide

Smiles: O=C(NN1C(=O)[C@@H]2[C@@H]([C@@H]3C=C[C@H]2[C@H]2C[C@@H]32)C1=O)C1C=CC(=CC=1)C(F)(F)F

InChiKey: CSKDFZIMJXRJGH-VWLPUNTISA-N

InChi: InChI=1S/C19H15F3N2O3/c20-19(21,22)9-3-1-8(2-4-9)16(25)23-24-17(26)14-10-5-6-11(13-7-12(10)13)15(14)18(24)27/h1-6,10-15H,7H2,(H,23,25)/t10-,11+,12+,13-,14-,15+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.