HS-PEG3-CH2CH2NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1189760-69-7

Molecular Weight: 209.31

Formula: C8H19NO3S

Chemical Name: 2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethane-1-thiol

Smiles: NCCOCCOCCOCCS

InChiKey: UKWCLHRGJBPEJY-UHFFFAOYSA-N

InChi: InChI=1S/C8H19NO3S/c9-1-2-10-3-4-11-5-6-12-7-8-13/h13H,1-9H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.