RPA32 (3E7) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3043-50, MB3043-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P15927

Host: Mouse

Reactivity: Human

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG2b

Bioworld Molecular Weight: Calculated MW: 29 kDa; Observed MW: 32 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of RPA32/RPA2 in MCF-7, Hela and HUVEC lysates using RPA32/RPA2 antibody., Immunocytochemistry analysis of RPA32 in HeLa using RPA32/RPA2 antibody., Immunoprecipitation analysis of RPA32 in Hela lysates using RPA32/RPA2 antibody.

Alternative Name: 60S acidic ribosomal protein P1; AA409079; AI325195; AU020965; HSSB; ik:tdsubc_2g1; M(2)21C; MGC137236; OTTHUMP00000004008; p32; p34; RCJMB04_6d17 replication protein A2; 32kDa; REPA 2; REPA1; REPA2; Replication factor A protein 2; Replication protein A 32 kDa subunit; Replication protein A 32kDa subunit; Replication protein A 34 kDa subunit; Replication protein A; replication protein A1 (70kD); Replication Protein A2 (32kDa); Replication protein A2 32kD; Replication protein A2 32kDa; Replication protein A2; Replication protein A2; 32kDa; RF A; RF-A protein 2; Rf-A2; RFA; RFA2_HUMAN; RP A; RP-A p32; RP-A p34; RP21C; RPA 2; RPA 32; RPA; RPA2; RPA32; RPA34; RPA70; RpLP1; RpP2; xx:tdsubc_2g1; zgc:109822.

Immunogen: Purified recombinant human RPA32/RPA2 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified