MerTK/Tyro3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4478-50, ES4478-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008],

Alternate Name: MERTK; MER; Tyrosine-protein kinase Mer; Proto-oncogene c-Mer; Receptor tyrosine kinase MerTK; TYRO3; BYK; DTK; RSE; SKY; Tyrosine-protein kinase receptor TYRO3; Tyrosine-protein kinase DTK; Tyrosine-protein kinase RSE; Tyrosine-protein kin

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human MER/SKY. AA range:716-765

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 97kD

Human Gene ID: 10461/7301

Human SWISS Prot NO: Q12866/Q06418

Subcellular Location: Cell membrane; Single-pass type I membrane protein.

Research Use Only