Cleaved-MMP-3 (F100) Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA23516-50, RA23516-100 Citations, Manuals and MSDS Available upon request. Background: matrix metallopeptidase 3 (MMP3) Homo sapiens Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications. Alternative Names: MMP3; STMY1; Stromelysin-1; SL-1; Matrix metalloproteinase-3; MMP-3; Transin-1 Applications: WB; ELISA Species Cross-Reactivity: Human; Rat; Mouse GeneID (Human): 4314 Protein MW (KDa): 43 SWISS: P08254 Source: Rabbit Research Use Only