OPRD1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90987-50, BS90987-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P41143(Human) P32300(Mouse) P33533(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, FC

All Applications: WB:1:1,000
FC:1:50-1:100

Background: Endogenous opioid peptides and opiates, like morphine, transmit their pharmacological effects through membrane bound opioid receptors. Pharmacological studies and molecular cloning have led to the identification of three different types of opioid receptor, mu-type, delta-type and kappa-type, also designated MOR-1, DOR-1 and KOR-1, respectively. MOR-1 is a receptor for beta-endorphin, DOR-1 is a receptor for enkephalins, and KOR-1 is a receptor for dynorphins. The three opioid receptor types are highly homologous and belong to the superfamily of G protein-coupled receptors. Opioid receptors have been shown to modulate a range of brain functions, including instinctive behavior and emotions. This regulation is thought to involve the inhibition of neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: OPRD1 polyclonal antibody detects endogenous levels of OPRD1 protein.

Bioworld Molecular Weight: 40 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of OPRD1 on different lysates using anti-OPRD1 antibody at 1/1,000 dilution.
Positive control:
Lane 1: HUVEC
Lane 2: Rat brain, Flow cytometric analysis of SH-SY-5Y cells with OPRD1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody

Alternative Name: D-OR-1, DOR-1, OPRD1, D-OR-1, Delta type opioid receptor, Delta type opioid receptor DOR 1, Delta type opioid receptor DOR1, Delta-type opioid receptor, DOR 1, DOR-1, DOR1, mDOR, Nbor, Opioid receptor delta 1, OPRD 1, OPRD, OPRD, Oprd1,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified