CHP2 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA23341-50, RA23341-100 Citations, Manuals and MSDS Available upon request. Background: calcineurin like EF-hand protein 2 (CHP2) Homo sapiens This gene product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+/H+ exchange activity. This protein shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988) . This gene was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520. [provided by RefSeq, Jul 2013], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications. Alternative Names: CHP2; HCA520; Calcineurin B homologous protein 2; Hepatocellular carcinoma-associated antigen 520 Applications: WB; ELISA Species Cross-Reactivity: Human; Mouse; Rat GeneID (Human): 63928 Protein MW (KDa): 22 SWISS: O43745 Source: Rabbit Research Use Only