CB2 receptor agonist 3 is a robust and selective CB2 cannabinoid agonist with Kis of 7.6 and 900 nM for CB2 and CB1, respectively. CB2 receptor agonist 3 significantly increases P-ERK 1/2 expression in HL-60 cells.

Product information

CAS Number: 919077-81-9

Molecular Weight: 440.36

Formula: C24H23Cl2N3O

Chemical Name: N-cyclohexyl-1-(2,4-dichlorophenyl)-6-methyl-1H,4H-indeno[1,2-c]pyrazole-3-carboxamide

Smiles: CC1=CC2CC3=C(C=2C=C1)N(N=C3C(=O)NC1CCCCC1)C1=CC=C(Cl)C=C1Cl

InChiKey: SPEFJYZGXZENAF-UHFFFAOYSA-N

InChi: InChI=1S/C24H23Cl2N3O/c1-14-7-9-18-15(11-14)12-19-22(24(30)27-17-5-3-2-4-6-17)28-29(23(18)19)21-10-8-16(25)13-20(21)26/h7-11,13,17H,2-6,12H2,1H3,(H,27,30)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

CB2 receptor agonist 3 (Compound 2a) is also shown to be agonist in an in vitro model based on human promyelocytic leukemia HL-60 cells.

Products are for research use only. Not for human use.